Hysterosalpingo Foam Sonography (HyFoSy), is an attractive alternative for tubal patency assessment and diagnosis
in subfertile women or women with known or suspected infertility. 1,2
Easy to perform and interpret in the gynecological office. It is also well tolerated by patients.
Dr. Ana Belén Garrido
Hospital Universitario de Torrejón Torrejón de Ardoz, Spain
I performed almost 300 HyFoSy procedures. It is easy to perform and well tolerated.
Dr. M.Inmaculada Mateos
Hospital de Galdakao-Usansolo Galdakao (Bizkaia), Spain
I have an excellent experience with ExEm Foam and I’m very satisfied with the product.
Dr. Laura Parziale
Hôpital du Jura 2800 Dolémont, Switzerland
Tubal patency assessment procedures timeline
1910
Laparoscopy: Jacobaeus (1910), Palmer (1947).
1910
First HSG is performed (Carey).
1966
Emergence of ultrasound based techniques with saline infusion sonography (SIS) (Corfman and Taylor).
1993
Introduction of Hysterosalpingo Contrast Sonography (HyCoSy) (Deichert), a patient friendly ultrasound technique. However, the common contrast medium Echovist® (Schering AG, Berlin, Germany) was taken out of market and replaced by saline and air. Saline and air which accuracy is not comparable to HSG, is now the mostly used alternative.6
2011
Introduction of Hysterosalpingo Foam Sonography (HyFoSy) (Exalto and Emanuel), an in-office procedure for tubal patency testing in women with known or suspected infertility or subfertility. ExEm® Foam is the medium used in HyFoSy.
2017
HyFoSy proven accuracy and minimum invasiveness. Studies suggested that, with proper imaging technique, HyFoSy with ExEm® Foam does not significantly differ from laparoscopy with dye and has the ability to achieve significantly higher accuracy than 2D saline and air7.
2022
HyFoSy, the future of tubal patency assessment. The foam study, a large randomized control study found that HyFoSy leads to similar pregnancy outcomes, compared with HSG as first-choice patency test. Then it also found that HyFoSy is experienced as significantly less painful than HSG.5
2017
HyFoSy proven accuracy and minimum invasiveness. Studies suggested that, with proper imaging technique, HyFoSy with ExEm® Foam does not significantly differ from laparoscopy with dye and has the ability to achieve significantly higher accuracy than 2D saline and air 7 .
We serve Sie Ihren Platz für eine gratis Schulung über Hysterosalpingo-Schaumsonographie-Verfahren (HyFoSy) und 3D-Beckenultraschall in Frankfurt am Main!
At ExEm® Women’s Health, we envision a better, simpler, and less invasive fertility journey for every woman. Driven by innovation and drawing on extensive expertise and experience, we identify and develop women’s health products that better meet the needs of today’s women and healthcare professionals of the world.
1. Ludwin I., Ludwin, A. et al. Accuracy of hysterosalpingo-foam sonography in comparison to hysterosalpingo-contrast sonography with air/saline and to laparoscopy with dye. Human Reproduction 2017, 32(4):758–69.
2. Riganelli L., Casorelli A. et al. Ultrasonography reappraisal of tubal patency in assisted reproduction technology patients: comparison between 2D and3D-sonohysterosalpingography. A pilot study. Minerva Ginecologica 2018, 70(2):123-28.
3. Reis MM, Soares SR, Cancado ML, Camargos AF. Hysterosalpingo contrast sonography (HyCoSy) with SH U 454 (Echovist) for the assessment of tubal patency. Hum Reprod. 1998;13(11):3049 –52.
4. Nienke van Welie, Joukje van Rijswijk, Kim Dreyer, et al. Can hysterosalpingo-foam sonography replace hysterosalpingography as first-choice tubal patency test? A randomized non-inferiority trial, Human Reproduction, 2022; deac034, https://doi.org/10.1093/humrep/deac034.